Turns out if you RTFM you can avoid this issue.
I found a clue in this post where the author mentions the ports required. Further reading, the installation document provided on the Sitecore portal indicates the required ports.
Active Directory requires that port 389 is open by default:
389 — for client communications
445 — for Active Directory Profile Provider
After running some tests using
Test-NetConnection, I was able to confirm that the port is not open for the second domain controller.
- Remove profile settings for the second domain and live without those properties populating.
- Get port 445 opened.