I have recently encountered the question related to Windows 10 Fall Creators Update (1709) breaking Sitecore Commerce 8.2.1 Update 2 installs. I had a perfectly working Sitecore Commerce 8.2.1 Update 2 site. When I installed the Windows 10 Fall Creators Update, I started getting the error below. When I rolled back the Windows 10 Fall Creators Update, the site started working again. Has anyone found a cause or fix for this issue - other than rolling back the Windows 10 Update?

Server Error in '/' Application.

Error HRESULT E_FAIL has been returned from a call to a COM component.

Description: An unhandled exception occurred during the execution of the current web request. Please review the stack trace for more information about the error and where it originated in the code. 

Exception Details: System.Runtime.InteropServices.COMException: Error HRESULT E_FAIL has been returned from a call to a COM component.

Source Error: 
 

An unhandled exception was generated during the execution of the current web request. Information regarding the origin and location of the exception can be identified using the exception stack trace below.

Stack Trace: 
 

[COMException (0x80004005): Error HRESULT E_FAIL has been returned from a call to a COM component.]
   CommerceServer.Core.Interop.Profiles.ProfileServiceClass.Initialize(String sConfigStore, String sCatalog) +0
   CommerceServer.Core.Runtime.Profiles.ProfileContext..ctor(String profileServiceConnectionString, String providerConnectionString, String bdaoConnectionString, DebugContext debugContext) +808

[CommerceProfileSystemException: Failed to initialize profile service handle.]
   CommerceServer.Core.Runtime.Profiles.ProfileContext..ctor(String profileServiceConnectionString, String providerConnectionString, String bdaoConnectionString, DebugContext debugContext) +1385
   CommerceServer.Core.Runtime.CommerceContextFactory.CreateProfileContext() +939
   CommerceServer.Core.Runtime.CommerceContextFactory.get_ProfileContextSingleton() +116
   CommerceServer.Core.Runtime.Profiles.CommerceProfileModule.get_ModuleProfileContext() +129
   CommerceServer.Core.Runtime.Profiles.CommerceProfileModule.get_ProfileContext() +178
   Sitecore.Commerce.Connect.CommerceServer.Pipelines.CommerceProfileProcessor.Begin(CommerceProfileModule module) +25
   Sitecore.Commerce.Connect.CommerceServer.Pipelines.CommerceBaseModuleProcessor`1.BeginRequest(PipelineArgs args) +92
   Sitecore.Commerce.Connect.CommerceServer.Pipelines.CommerceBaseModuleProcessor`1.Init(PipelineArgs args) +176
   (Object , Object[] ) +74
   Sitecore.Pipelines.CorePipeline.Run(PipelineArgs args) +469
   Sitecore.Pipelines.DefaultCorePipelineManager.Run(String pipelineName, PipelineArgs args, String pipelineDomain) +22
   Sitecore.Nexus.Web.HttpModule.Application_Start() +288
   Sitecore.Nexus.Web.HttpModule.Init(HttpApplication app) +670
   System.Web.HttpApplication.RegisterEventSubscriptionsWithIIS(IntPtr appContext, HttpContext context, MethodInfo[] handlers) +581
   System.Web.HttpApplication.InitSpecial(HttpApplicationState state, MethodInfo[] handlers, IntPtr appContext, HttpContext context) +172
   System.Web.HttpApplicationFactory.GetSpecialApplicationInstance(IntPtr appContext, HttpContext context) +418
   System.Web.Hosting.PipelineRuntime.InitializeApplication(IntPtr appContext) +369

[HttpException (0x80004005): Failed to initialize profile service handle.]
   System.Web.HttpRuntime.FirstRequestInit(HttpContext context) +534
   System.Web.HttpRuntime.EnsureFirstRequestInit(HttpContext context) +111
   System.Web.HttpRuntime.ProcessRequestNotificationPrivate(IIS7WorkerRequest wr, HttpContext context) +718