To disable a single patch file, you can do one of two things:

**Option1:** Navigate to the patch file in the file system, and rename it to end in something other than .config. For example, rename `Sitecore.Analytics.Config to Sitecore.Analytics.Config.Disabled`.


**Option2**: Add the patch file to a `<loadOrder> section and add the `mode="Off"` attribute. 
For example: 
``<add path="Sitecore.Analytics.Config" type="File" mode="Off" />``

**Note**: Option 2 will only work with 9.0 or later versions.